DHT and Hair Loss

Do you know what causes hair loss?

DHT and Hair Loss

DHT and Hair Loss

Many doctors agree that Dihydrotestosterone (DHT) in the scalp is the main contributor of hair loss. DHT is created by testosterone which is why hair loss mainly affects males. When testosterone is naturally converted to DHT, the result is hair loss.

Dihydrotestosterone, i.e. DHT is an active metabolite of the hair hormone testosterone that is formed in the adrenal gland, hair follicles, prostate glands and testes. Dihydrotestosterone i.e. DHT belongs to the class of compound known as androgens, which is commonly known as the testoids or androgenic hormone.

When Males produce the DHT this helps in the formation of the male specific characteristic such as development of the body hair, development of the facial hair, thickness of the voice and etc. DHT Blockers work to prevent the effects of this hormone after the puberty phase is completed, and the abundance of this compound is no longer needed in men.

Hormonal changes are the #1 factor in hair loss of both men and women. This is mainly because of the hair follicles having a greater number of Androgen’s receptors (regulators of gene expressions) for the DHT to attach to.

Androgen is the male hormone that plays a very important role in both hair loss and hair growth. This metabolism of androgen gets involved with an enzyme, the 5 alpha reductase which tends to combine with the male hormone, testosterone to give DHT (Dihydrotestosterone). This DHT is the natural metabolite of the human body that is the main reason for hair loss.

The most important structure of a hair follicle is the dermal papilla, which is responsible for hair growth. The cell of this dermal papilla divides and differentiates to form a new hair follicle. As this dermal papilla lies in direct contact with blood capillaries of the skin, it is responsible for deriving nutrients for hair follicle growth. This dermal papilla has many receptors for androgen’s; where men have more androgenic receptors here than women.

It is very important for a person to have proper nutrition to maintain hair. So when DHT reaches the hair follicles and dermal papilla, it tends to prevent proteins, vitamins and minerals from providing the needed nourishment to sustain life in the hair of these follicles. With this, the hair follicles tend to reproduce at a slower rate and this in turn either shortens the growing phase of the hair follicles or lengthens its resting stage.

DHT is also responsible for shrinking hair follicle with which the hair follicle gets smaller and finer. This is referred to as miniaturization with which the hair ultimately falls off. This is how DHT is responsible for about 95% of hair loss. The men or women who lose more hair are those who are genetically pre-disposed in producing more DHT than others.

In addition to all this, DHT tends to create a wax like substance around the hair roots and it is this accumulation of DHT in the hair follicles and roots that gives rise to male and female pattern hair loss. There is a type of treatment that blocks the synthesis of DHT at molecular level to cure both male pattern and female pattern hair loss. This is done by using one of the many natural DHT blockers and drugs that are used for medical hair restoration.

Understanding the role of the dihydrotestosterone both in the male and the female pattern baldness, the researchers have discovered some unique way to prevent this hormone to act on the receptors in the scalp. Products that prevent those hormones are often called DHT Blockers.

Researches have established that DHT is 30 times more potent as compared to the testosterone hormone. This is due to the fact that it has an increased affinity for the androgen receptor.

However, there are many topical DHT blockers and inhibitors that are easily available in the open market under different brand names – being manufactured and marketed by different companies. Advica, Procerin, Provillus for men and Provillus for women are some of the DHT inhibitors (Blockers).

Ketoconezole is a synthetic drug that has some wondrous properties of both anti-fungal and 5-alfa reductase inhibitor. 5-alfa reductase is basically an enzyme that converts the male sex hormone (testosterone) into DHT.

Saw Palmetto is one of the most potent herbal or natural DHT blockers, which proves to be far cheaper than most of the other contemporary DHT inhibitors in the market, but may not be as effective for some people as the products listed above. Blocking DHT is effective in slowing the effects of the hormone on the follicle, slowing hair loss. Some hair loss shampoo formulas report using Saw Palmetto in their ingredients list as a topical inhibitor for DHT.

It is believed that DHT also participates in the development of acne and male pattern baldness. Women suffering from the high level of the dihydrotestosterone or DHT mostly develop some androgynous male secondary sex properties such as hair growth just above their upper lips, more developed muscles and thick voice. Although the exact reasons have yet to be discovered it has been established by the researchers that the overproduction of DHT leaves the subjects exposed to the risks of prostate cancer and benign prostatic hyperplasia BHP.

In simple terms the hair follicles need to block DHT build up and this will keep the hair on your head where it belongs.

DHT and Hair Loss in Men

Hair loss and thinning hair have been sensitive issues for men throughout time. Recently, medical science has finally identified the main cause of hair loss. Now, it is a known medical fact that hair loss stems from both genetic and hormonal causes. Androgenic Alopecia or “male pattern hair loss” is implicated in 95% of hair loss cases. The key is a hormonal byproduct called DHT (dihydrotestostrone). The more DHT that gets put into your body, the more your hair follicles become thinner and finer until the hair is permanently lost.

DHT and Hair Loss in Women

Female Pattern Baldness (FPB) affects 1 out of every 4 women in the United States and Canada. Recent findings have found that the incidence of FPB has been reported to be as low as 8% and as high as 87%. And, it does appear to be as common for women as for men. Most often, menopause is the most frequent time for female hair loss to become apparent.

For women hair loss can be even more troubling than for men. Female hair loss is not generally accepted as part of the normal aging process. Society has come to expect a thick, luxurious head of hair as part of the attractiveness in women.

While men and women can both experience pattern baldness, they typically do not lose their hair in the same order or appearance.

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